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Expert in Lipases, Biointerfaces, Instrumentation, Interaction of Drugs and Proteins with Lipids, Monolayers
Available for your Consulting and Expert Witness Needs
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| Summary of Expertise: |
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Primary Expertise Areas:
(links show more experts in each area)
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Expertise Description: |
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adsorption expert
cholesterol esterase expert
lipase expert
monomolecular film expert |
LIPASES. Expert has spent most of his scientific career studying the regulation of lipases and other enzymes which function at oil-water interfaces. The emphasis of his work has been placed upon studying the role of lipid-lipid and lipid-protein interactions in the control of lipolysis at the molecular level. Lipids with which he has been particularly interested are lecithin, diacylglycerol, fatty acid, and cholesterol. CHOLESTEROL ESTERASES. As a part of his study of lipases in general, Expert has devoted considerable effort to the study of cholesterol esterases. He notes that these are important enzymes in mammalian cholesterol homeostasis. The mammalian form most studied by Expert is that which belongs to the cholinesterase gene family. This is also known as bile-salt-stimulated lipase, lysophospholipase, carboxylester lipase, sterol ester hydrolase, and non-specific lipase. ADSORPTION. Expert has extensive expertise in studying enzyme, peptide and drug adsorption to lipid-water interfaces. He notes that this has been necessitated by his lipase interest because lipases must adsorb to the lipid-water interface before they can act on substrates in it. The emphasis of his work on adsorption has been the retention of catalytic activity. Examples of this include the lack of protein denaturation and the role of the 2-dimensional organization of lipids in regulating protein adsorption. His recent focus has been on the application of percolation theory to the regulation of lipase adsorption and catalysis. MONOMOLECULAR FILMS. Expert has made extensive use of monolayer techniques as a model lipid-water interface for studying lipase adsorption and catalysis. For analyzing such data, he has developed mathematical algorithms to characterize the surface potential-surface pressure-area characteristics of mixtures of lipids in monomolecular films. Lipids of interest to him have been phospholipids, acylglycerols, fatty acids, and cholesterol esters. Expert has developed automated instrumentation to facilitate the study of lipid-lipid and lipid-protein interactions in monomolecular films. He has emphasized the detection and elimination of surface-active impurities in this work. His goal in doing so has been to insure the accuracy and precision of his data.
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| Show Secondary and Basic Areas of Expertise |
Localities:
Expert may consult nationally and internationally, and is also local to the following cities: Minneapolis, Minnesota; Saint Paul, Minnesota; Rochester, Minnesota; Burnsville, Minnesota; Eden Prairie, Minnesota; Minnetonka, Minnesota; Waterloo, Iowa; and La Crosse, Wisconsin.
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Degree |
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Subject |
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Institution |
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1971
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PhD
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Biochemistry,
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Michigan State University
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1966
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BA
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Chemistry,
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DePauw University
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Department |
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Title |
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Responsibilities |
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1981 to
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(Undisclosed University)
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The Hormel Institute
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Professor
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Responsible for creating, funding executing research projects on lipid-lipid interactions as regulators of the interactions of enzymes, peptides and drugs with membranes
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1977 to 1981
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Expert's University, The Hormel Institute
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The Hormel Institute
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Associate Professor
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1973 to 1977
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Expert's University, The Hormel Institute
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The Hormel Institute
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Assistant Professor
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1999 to
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(Undisclosed University)
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President
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Developing an marketing software, consulting and instrumentation in the area of biophysical surface chemistry
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Associations/Societies
Expert is a member of the American Chemical Society, the American Society of Biological Chemists, the Council on Atherosclerosis of the American Heart Association, the American Association for the Advancement of Science, and the Biophysical Society. In addition to his primary appointment, Expert is an Associate Faculty member of the self assembly processes group of the University of Minnesota's Center for Interfacial Engineering.
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Professional Appointments
He is on the Editorial Board of the Journal of Lipid Research. In addition, he has been an Established Investigator of the American Heart Association from 1978-83.
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Publications and Patents
He has published over 60 technical papers.
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As a member of the Intota consultant network,
Expert is a specialist who provides technical consulting to corporate, legal and government clients. Expert provides professional consulting as a Lipases Consultant, Biointerfaces Consultant, Instrumentation Consultant, Interaction of Drugs Consultant and Proteins with Lipids Consultant, Monolayers Consultant. Expert may consult as an independent consultant or as a member of a consultancy, consulting company,
or consulting firm. Consultants service will be covered by a consulting contract.
Ask an expert initial screening questions and ask the experts services particulars, by simply submitting
an expert request.
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Intota experts can serve as expert witnesses or litigation consultants offering expert testimony, expert advice, litigation support,
forensic services, and related expert witness services. Expert can serve as an expert witness or litigation consultant in intellectual property (patent, trademark, trade secret, copyright),
product liability, and insurance matters. Expert may provide forensic expert witness testimony, litigation consulting services, forensic investigation,
and forensic testing if appropriate in litigation areas as a Lipases Expert Witness, Biointerfaces Expert Witness, Instrumentation Expert Witness, Interaction of Drugs Expert Witness and Proteins with Lipids Expert Witness, Monolayers Expert Witness.
Intota provides attorneys and legal professionals the opportunity to ask an expert initial screening questions and
ask the experts services particulars by submitting an expert request.
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| Language Skills: |
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| Foreign Language |
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Description |
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French and German
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Expert reads French and German.
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Expert serves as a resource to
Intota Market Research Services
for customized marketing research in industries or areas related to
Lipases, Biointerfaces, Instrumentation, Interaction of Drugs and Proteins with Lipids, Monolayers.
Experts are an invaluable source of overall industry insight as well as insight into specific companies and firms for
custom business to business (b2b) and industrial market research. Intota uses analyst and
consultant resources from Guideline whose Research Directors manage the research and analysis of the qualitative
and quantitative data as well as report writing for the custom studies. The methods and tools
used by Intota market research combine the insights of technical experts and industry insiders with secondary
research to provide the custom b2b and industrial market research you need.
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Expertise
